The Ultimate California Mission Road Trip
A complete itinerary for driving El Camino Real and visiting all 21 missions—with stops for food, wine, and beaches along the way.
21 Historic Missions Along El Camino Real
Stretching 600 miles from San Diego to Sonoma, California's 21 Spanish colonial missions represent one of America's most significant historic trails. Founded between 1769 and 1823, these missions shaped the history of the American West.
Short on time? These are the most impressive, best-preserved, and most historically significant missions to prioritize.
The complex history of the mission system—Spanish colonization, the Franciscan order, and the impact on Native peoples.
Each of California's 21 missions has its own character and history. Here are some of the most visited and best preserved.
The 'Jewel of the Missions'
6 guides
First of California's missions
4 guides
Queen of the Missions
5 guides
Father Serra's headquarters
5 guides
Mission in wine country
4 guides
San Francisco's oldest building
4 guides
Northernmost and last mission
3 guides
Most fully restored mission
4 guides
A car is essential for the Mission Trail. Highway 101 roughly follows El Camino Real and connects most missions. The full drive takes 10-12 hours without stops.
Highlights only: 3-4 days
Most missions: 7-10 days
All 21 missions: 2+ weeks (recommended)
Most missions charge $5-15 admission. Some are free. Annual passes available for state historic parks (La Purísima, Sonoma, others).
South to North: Start in San Diego
North to South: Start in Sonoma
LA-based: Start at San Juan Capistrano
Base yourself in mission towns: San Diego, Santa Barbara, San Luis Obispo, Carmel, or San Francisco for easy access to multiple missions.
Most photogenic: San Juan Capistrano, Santa Barbara, Carmel
Best gardens: San Juan Capistrano, Santa Barbara
Golden hour: West-facing missions in afternoon